PULMONARY VASCULAR EFFECTS OF TRINITROGLYCERIN AND ISOSORBIDE DINITRATE AFTER CARDIOPULMONARY BYPASS †
نویسندگان
چکیده
منابع مشابه
Vasodilator properties of nitroglycerin and isosorbide dinitrate during cardiopulmonary bypass.
In a placebo-controlled trial, we have studied the vasodilator properties of bolus doses of nitroglycerin (TNG) and isosorbide dinitrate (ISDN) in 32 patients during cardiopulmonary bypass with a constant pump flow. Blood volume of the venous reservoir and mean arterial pressure were recorded for 10 min after drug administration to detect changes in venous capacitance and arteriolar resistance,...
متن کاملComparison of Effects of Propofol and Isosorbide Dinitrate during Rewarming on Cardiopulmonary Bypass
OBJECTIVES Comparison of effects of propofol and isosorbide dinitrate during rewarming on cardiopulmonary bypass in patients undergoing coronary artery bypasses grafting. METHODS It was randomized prospective clinical trial. One hundred and twenty patient (120) undergoing CABG surgery were included in this study. Group-I (Study group, n=60): in which only propofol infusion used during rewarmi...
متن کاملClinical and circulatory effects of isosorbide dinitrate. Comparison with nitroglycerin.
In order to resolve current controversies on isosorbide dinitrate (ISDN), we employed a particularly sensitive testing protocol to evaluate effects of sublingual ISDN and nitroglycerin on the exercise capacity of patients with angina. Ten minutes after ISDN 21 of 23 patients exercised longer (average 2.7 minutes, P < 0.001) than after placebo. Benefit was evident in only a minority of patients ...
متن کاملDilation of coronary artery stenoses after isosorbide dinitrate in man.
The effect of isosorbide dinitrate (ISDN), 5 mg sublingually, on the diameters of coronary artery stenoses (n = 27) was examined in 20 patients. Another 18 patients with angiographically normal coronary arteries received the same amount of ISDN and were used as controls. Prestenotic and stenotic diameters were measured with a vernier calliper having an accuracy of 0.05 mm. The degree of stenosi...
متن کاملPulmonary vascular resistance before and after cardiopulmonary bypass. The effect of PaCO2.
To examine whether CPB influences pulmonary vascular sensitivity to CO2, we compared the effect of slight induced hypocarbia and hypercarbia on pulmonary circulation before and after CPB in ten mechanically ventilated patients undergoing CABG. Hypocarbia was produced by increasing tidal volume slightly and hypercarbia was then induced by adding CO2 to the inspired gas mixture. In another ten pa...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1993
ISSN: 0007-0912
DOI: 10.1093/bja/71.5.720